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Tuesday, October 6, 2020 | History

2 edition of Genetic factors affecting the reactivation of damaged bacteriophages. found in the catalog.

Genetic factors affecting the reactivation of damaged bacteriophages.

Thomas Lyle Kerr

Genetic factors affecting the reactivation of damaged bacteriophages.

by Thomas Lyle Kerr

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  • 20 Currently reading

Published .
Written in English


Edition Notes

Thesis (Ph. D.)--The Queens" University of Belfast, 1972.

The Physical Object
Pagination1 v
ID Numbers
Open LibraryOL21529750M

Bacteriophages are viruses that infect bacteria. As such, they have many potential uses for promoting health and combating disease. This book covers the many facets of phage-bacterial-human interaction in three sections: the role and impact of phages on natural bacterial communities, the potential to develop phage-based therapeutics and other aspects in which . Abstract. The study of bacteriophages has had a crucial influence on many areas of genetics and molecular biology. Part of the evidence for DNA as the genetic material came from phage T4, and the study of ΦX has played a significant role in the analysis of DNA : Brian W. Bainbridge.

Bacteriophages, viruses infecting bacteria, are uniformly present in any location where there are high numbers of bacteria, both in the external environment and the human body. Knowledge of their diversity is limited by the difficulty to culture the host species and by the lack of the universal marker gene present in all viruses. its genetic material into it. In , Alfred Hershey and Martha Chase used radioactive tracers to label proteins and DNA in bacteriophages. Only the DNA from the bacteriophage showed up in the infected bacterial cell. Hershey and Chase concluded that the genetic material of the bacteriophage was Size: KB.

Bacteriophages The Importance of Bacteriophages: Historical: Frederick Twort () and Felix d'Herelle () were the first to recognize viruses which infect bacteria, which d'Herelle called bacteriophages (eaters of bacteria). In the s and subsequent decades, pioneering virologists such as Luria, Delbruck and many others utilized these viruses as model systems to . A bacteriophage is a virus that infects bacteria. Bacteriophages, first discovered around , have played a unique role in viral biology. They are perhaps the best-understood viruses, yet at the same time, their structure can be extraordinarily complex. A bacteriophage is essentially a virus consisting of DNA or RNA that is enclosed within a Author: Regina Bailey.


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Genetic factors affecting the reactivation of damaged bacteriophages by Thomas Lyle Kerr Download PDF EPUB FB2

Various external physical and chemical factors, such as temperature, acidity, salinity, and ions, determine the occurrence, viability, and storage of bacteriophages and can inactivate a phage through damage of its structural elements (head, tail, envelope), lipid loss, and/or DNA structural changes (Ackermann et al.

).Cited by:   The influence of external factors on bacteriophages–review. Folia Microbiol. (Praha) 56 – /s [PMC free article] Kocharunchitt C., Ross T., McNeil D.

Use of bacteriophages as biocontrol agents to control Salmonella associated with seed sprouts. Int. by: Influence of Infected Cell Growth State on Bacteriophage Reactivation Levels.

to reactivate UV-damaged bacteriophages by dark repair at. F, G, and. Bacteriophage, also called phage or bacterial virus, any of a group of viruses that infect iophages were discovered independently by Frederick W. Twort in Great Britain () and Félix d’Hérelle in France ().

D’Hérelle coined the term bacteriophage, meaning “bacteria eater,” to describe the agent’s bacteriocidal ability. Many bacteriophages employ a mechanism rather like a hypodermic syringe to inject genetic material into the cell through a tail-like structure. Synthesis of proteins and nucleic acid: Bacterial.

Start studying Chapter 7: Genetic Transfer & Mapping in Bacteria and Bacteriophages. Learn vocabulary, terms, and more with flashcards, games, and other study tools. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ f eɪ dʒ /), is a virus that infects and replicates within bacteria and term was derived from "bacteria" and the Greek φαγεῖν (phagein), meaning "to devour".Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple.

Kutter, in Encyclopedia of Genetics, Bacteriophages were first described and named by Félix d'Herelle in (see D'Herelle, Félix); similar phenomena had been independently reported by Frederick Twort in though with little detail, and the two are jointly given credit for the discovery of the beginning, d'Herelle was interested in the possibility of using.

Bacterial viruses, or bacteriophages, are estimated to be the most widely distributed and diverse entities in the biosphere. From initial research defining the nature of viruses, to deciphering the fundamental principles of life, to the development of the science of molecular biology, phages have been 'model organisms' for probing the basic chemistry of life.

The influence of external factors on bacteriophages—review E. Jończyk & M. Kłak & R. Międzybrodzki & A. Górski Received: 16 September /Accepted: 8 February /Published online: 31 May # The Author(s) This article is published with open access at Abstract The ability of bacteriophages to survive underCited by: Bacteriophages were jointly discovered by Frederick Twort () in England and by Felix d'Herelle () at the Pasteur Institute in France.

Felix d'Herelle coined the term “Bacteriophage”. Bacteriophage means to eat bacteria, and are called so because virulent bacteriophage can cause the compete lysis of a susceptible bacterial culture. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.

Bacteriophages were formally discovered in the mid to late teens of the 20 th century, with the first publication coming out in and then a second in They were early on speculated to be viral, but their dominant property was an ability to macroscopically "eat" bacterial cultures, specifically by reducing the cloudiness (turbidity.

Bacteriophages, Part A. Edited by Małgorzata Łobocka, Wacław T. Szybalski. Vol Pages () Bacteriophage-Encoded Bacterial Virulence Factors and Phage–Pathogenicity Island Interactions Book chapter Full text access Chapter 4 - Bacteriophage-Encoded Bacterial Virulence Factors and Phage–Pathogenicity Island.

If there's a mutation in the gene that the bacteriophages use to disrupt bacterial membranes, the toxin merely builds up inside the E. coli. "Phages not only disseminate virulence genes but also regulate the production of the virulence factors," says Waldor.

This discovery has brought a disconcerting fact about certain antibiotics to light. In a study of factors affecting the EOP of phages for Lc. lactis subsp cremoris strains AM1 and AM2, the author found that if adsorption of phage to host cells took place at 20°C, prior to agar addition, a significant increase in EOP was obtained (Table 3).

Plaque diameter was slightly increased, also. Bacteriophages consist of protein coats surrounding the viral genetic material. The genetic material can be either DNA or RNA.

The protein coat serves to protect the viral genome and to deliver it into the host cell to be infected. Bacteriophages are "bacteria eaters" in that they are viruses that infect and destroy mes called phages, these microscopic organisms are ubiquitous in nature.

In addition to infecting bacteria, bacteriophages also infect other microscopic prokaryotes known as infection is specific to a specific species of bacteria or : Regina Bailey. The article "Factors affecting plaque formation by bacteriophages" has been updated to reflect research by Luhtanen et al., on cold-active phages.

Phage therapy or viral phage therapy is the therapeutic use of bacteriophages to treat pathogenic bacterial infections.

Bacteriophages, known as phages, are a form of viruses. Phages attach to bacterial cells, and inject a viral genome into the cell.

The viral genome effectively replaces the bacterial genome, halting the bacterial infection. The bacterial cell causing the infection is. Electron micrograph E. coli bacteriophage T4. Bacteriophages are viruses that infect bacteria. They are a major agent of horizontal gene transfer between bacteria—a concept covered in AP® Biology and other biology classes.

What students may not be aware of is the role bacteriophages play in human disease. You would not expect bacteria.Charon 34 and Charon These vectors will accept fragments kb (kilobases) long. M13 as cloning vector for DNA sequencing. M13 is a filamentous bacteriophage of E.

coli and contains a kb long single stranded circular DNA. M13 phage has been variously modified to give rise to a MP13 mp series of cloning vectors which can be used for cloning of a wide variety of DNA .Phage therapy - the use of bacteriophages as anti-bacterial agents - may offer an alternative treatment for bacterial infections.

Phages have many potential applications in human medicine, as well as in dentistry, veterinary science, agriculture, and food : $